Chemicals and Drugs

Subfamily D ATP Binding Cassette Transporter

A sub-family of ATP-binding cassette transporters that localize to the membranes of PEROXISOMES; ENDOPLASMIC RETICULUM; and LYSOSOMES. Members contain a transmembrane domain in their N-terminal half and generally function as homodimers in the transport of LIPIDS; BILE ACIDS; and VITAMIN B12. Mutations in some ABCD transporter genes are associated with PEROXISOMAL DISORDERS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A sub-family of ATP-binding cassette transporters that localize to the membranes of PEROXISOMES; ENDOPLASMIC RETICULUM; and LYSOSOMES. Members contain a transmembrane domain in their N-terminal half and generally function as homodimers in the transport of LIPIDS; BILE ACIDS; and VITAMIN B12. Mutations in some ABCD transporter genes are associated with PEROXISOMAL DISORDERS.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

7 entry terms
  • ABC Transporter Subfamily D
  • ABCD Proteins
  • ABCD Transporters
  • ATP Binding Cassette Transporter, Sub-Family D
  • ATP Binding Cassette Transporter, Subfamily D
  • ATP Binding Cassette Transporter, Sub Family D
  • Transporters, ABCD

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2019 (2018)

MeSH Record

Previous Indexing

  • ATP-Binding Cassette Transporters (1998-2017)

MeSH Hierarchy

Tree Numbers

  1. D09w.400w.430w.890w.020w.419
  2. D12.776w.157w.530w.100w.209
  3. D12.776w.395w.550w.020w.419
  4. D12.776w.543w.550w.192w.419
  5. D12.776w.543w.585w.100w.209

AMA Style

References

  1. National Library of Medicine. Subfamily D ATP Binding Cassette Transporter. Medical Subject Headings (MeSH). 2026. Unique ID D000074061. http://id.nlm.nih.gov/mesh/2026/D000074061
  2. Subfamily D ATP Binding Cassette Transporter. In: Wikidata. https://www.wikidata.org/wiki/Q113190943