Chemicals and Drugs

Strophanthidin

3 beta,5,14-Trihydroxy-19-oxo-5 beta-card-20(22)-enolide. The aglycone cardioactive agent isolated from Strophanthus Kombe, S. gratus and other species; it is a very toxic material formerly used as digitalis. Synonyms: Apocymarin; Corchorin; Cynotoxin; Corchorgenin.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

3 beta,5,14-Trihydroxy-19-oxo-5 beta-card-20(22)-enolide. The aglycone cardioactive agent isolated from Strophanthus Kombe, S. gratus and other species; it is a very toxic material formerly used as digitalis. Synonyms: Apocymarin; Corchorin; Cynotoxin; Corchorgenin.

Chemical Identity

Chemical Information

Molecular Formula
C23H32O6
Molecular Weight
404.5 g/mol
CAS Registry No.
66-28-4
IUPAC Name
(3S,5S,8R,9S,10S,13R,14S,17R)-3,5,14-trihydroxy-13-methyl-17-(5-oxo-2H-furan-3-yl)-2,3,4,6,7,8,9,11,12,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-10-carbaldehyde
InChIKey
ODJLBQGVINUMMR-HZXDTFASSA-N
SMILES
C[C@]12CC[C@H]3[C@H]([C@]1(CC[C@@H]2C4=CC(=O)OC4)O)CC[C@]5([C@@]3(CC[C@@H](C5)O)C=O)O
MeSH Unique ID
D013327
Source
PubChem CID 6185

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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MeSH Record

Synonyms

6 entry terms
  • Convallatoxigenin
  • Corchsularin
  • Cymarigenin
  • K-Strophanthidin
  • K Strophanthidin
  • KStrophanthidin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

a cardioactive agent

MeSH Record

History Note

77(75); was see under STROPHANTHINS 1975-76, was see under CARDANOLIDES 1968-74

MeSH Record

Previous Indexing

  • Cardanolides (1968-1974)

MeSH Hierarchy

Tree Number

  1. D04w.210.500w.155.580w.130.750w.800w

AMA Style

References

  1. National Library of Medicine. Strophanthidin. Medical Subject Headings (MeSH). 2026. Unique ID D013327. http://id.nlm.nih.gov/mesh/2026/D013327
  2. Strophanthidin. In: Wikipedia. https://en.wikipedia.org/wiki/K-Strophanthidin
  3. Strophanthidin. In: Wikidata. https://www.wikidata.org/wiki/Q1718068
  4. Strophanthidin. In: PubChem Compound. CID 6185. https://pubchem.ncbi.nlm.nih.gov/compound/6185