Phenomena and Processes

Sterile Alpha Motif

A putative protein interaction module, approximately 70 amino acids long, that forms a small five-helix bundle with two large interfaces which may homo- and hetero-oligomerize, or bind non-sterile-alpha motif targets. The sterile alpha motif is present in a wide variety of eukaryotic proteins that function in diverse biological processes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A putative protein interaction module, approximately 70 amino acids long, that forms a small five-helix bundle with two large interfaces which may homo- and hetero-oligomerize, or bind non-sterile-alpha motif targets. The sterile alpha motif is present in a wide variety of eukaryotic proteins that function in diverse biological processes.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

6 entry terms
  • SAM Domain
  • Sterile Alpha Motif Domain
  • Motif, Sterile Alpha
  • Motifs, Sterile Alpha
  • SAM Domains
  • Sterile Alpha Motifs

MeSH Record

Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

MeSH Record

History Note

2017

MeSH Record

Previous Indexing

  • Protein Structure, Tertiary (1998-2016)

MeSH Hierarchy

Tree Numbers

  1. G02.111.570.820w.709.275.500.898w
  2. G02.111.570.820w.709.275.750w.500.813w

AMA Style

References

  1. National Library of Medicine. Sterile Alpha Motif. Medical Subject Headings (MeSH). 2026. Unique ID D000071682. http://id.nlm.nih.gov/mesh/2026/D000071682
  2. Sterile Alpha Motif. In: Wikipedia. https://en.wikipedia.org/wiki/Sterile_alpha_motif
  3. Sterile Alpha Motif. In: Wikidata. https://www.wikidata.org/wiki/Q24721736