Structured Summary
Abstract
A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.
MeSH Record
Classification
Related Concepts
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MeSH Record
Synonyms
19 entry terms
- Lap18 Protein
- Leukemia-Associated Phosphoprotein p18
- Metablastin
- Oncoprotein 18
- Op18 Phosphoprotein
- Phosphoprotein p18
- Phosphoprotein p19
- Prosolin
- Leukemia Associated Phosphoprotein p18
- Phosphoprotein, Op18
- p18, Leukemia-Associated Phosphoprotein
- p18, Phosphoprotein
- p19, Phosphoprotein
- Alpha-Stathmin
- Beta-Stathmin
- Op18a Protein
- Op18b Protein
- Alpha Stathmin
- Beta Stathmin
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1987)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Stathmin. Medical Subject Headings (MeSH). 2026. Unique ID D050777. http://id.nlm.nih.gov/mesh/2026/D050777
- Stathmin. In: Wikidata. https://www.wikidata.org/wiki/Q4441290