Chemicals and Drugs

Staphylococcal Protein A

A protein present in the cell wall of most Staphylococcus aureus strains. The protein selectively binds to the Fc region of human normal and myeloma-derived IMMUNOGLOBULIN G. It elicits antibody activity and may cause hypersensitivity reactions due to histamine release; has also been used as cell surface antigen marker and in the clinical assessment of B lymphocyte function.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A protein present in the cell wall of most Staphylococcus aureus strains. The protein selectively binds to the Fc region of human normal and myeloma-derived IMMUNOGLOBULIN G. It elicits antibody activity and may cause hypersensitivity reactions due to histamine release; has also been used as cell surface antigen marker and in the clinical assessment of B lymphocyte function.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

2 entry terms
  • Protein A
  • Protein A, Staphylococcal

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

78

MeSH Record

Previous Indexing

  • Antigens, Bacterial (1971-1977)
  • Bacterial Proteins (1966-1977)
  • Staphylococcus (1966-1975)
  • Staphylococcus aureus (1976-1977)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Staphylococcal Protein A. Medical Subject Headings (MeSH). 2026. Unique ID D013205. http://id.nlm.nih.gov/mesh/2026/D013205
  2. Staphylococcal Protein A. In: Wikidata. https://www.wikidata.org/wiki/Q72508846