Structured Summary
Abstract
The second enzyme in the committed pathway for CHOLESTEROL biosynthesis, this enzyme catalyzes the first oxygenation step in the biosynthesis of STEROLS and is thought to be a rate limiting enzyme in this pathway. Specifically, this enzyme catalyzes the conversion of SQUALENE to (S)-squalene-2,3-epoxide.
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Classification
Broader headings
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MeSH Record
Synonyms
4 entry terms
- Squalene Epoxidase
- Squalene Monooxygenase (2,3-Epoxidizing)
- Epoxidase, Squalene
- Monooxygenase, Squalene
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1980); use ETHERS, CYCLIC 1970-1979
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AMA Style
References
- National Library of Medicine. Squalene Monooxygenase. Medical Subject Headings (MeSH). 2026. Unique ID D050603. http://id.nlm.nih.gov/mesh/2026/D050603
- Squalene Monooxygenase. In: Wikipedia. https://en.wikipedia.org/wiki/Squalene_monooxygenase
- Squalene Monooxygenase. In: Wikidata. https://www.wikidata.org/wiki/Q414248