Chemicals and Drugs

Splicing Factor U2AF

An RNA splicing factor that performs a critical function in both constitutive and enhancer-dependent RNA SPLICING. It recruits RIBONUCLEOPROTEIN, U2 SMALL NUCLEAR to the splice site and mediates interactions between it, the RNA molecule, and other splicing factors for accurate 3'-splice site selection.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An RNA splicing factor that performs a critical function in both constitutive and enhancer-dependent RNA SPLICING. It recruits RIBONUCLEOPROTEIN, U2 SMALL NUCLEAR to the splice site and mediates interactions between it, the RNA molecule, and other splicing factors for accurate 3'-splice site selection.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • U2AF 65
  • U2AF Splicing Factor
  • U2AF(65)
  • Factor U2AF, Splicing
  • Factor, U2AF Splicing
  • Splicing Factor, U2AF
  • U2AF, Splicing Factor

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2017 (1993)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.725w.829w.750
  2. D12.776w.664w.962w.829w.750

AMA Style

References

  1. National Library of Medicine. Splicing Factor U2AF. Medical Subject Headings (MeSH). 2026. Unique ID D000072668. http://id.nlm.nih.gov/mesh/2026/D000072668
  2. Splicing Factor U2AF. In: Wikidata. https://www.wikidata.org/wiki/Q77302521