Diseases

Spinal Muscular Atrophy

A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

42 entry terms
  • Muscular Atrophy, Spinal
  • Spinal Amyotrophy
  • Amyotrophies, Spinal
  • Amyotrophy, Spinal
  • Atrophy, Spinal Muscular
  • Spinal Amyotrophies
  • Adult Spinal Muscular Atrophy
  • Adult-Onset Spinal Muscular Atrophy
  • Amyotrophy, Neurogenic Scapuloperoneal, New England Type
  • Bulbospinal Neuronopathy
  • Distal Spinal Muscular Atrophy
  • Hereditary Motor Neuronopathy
  • Muscular Atrophy, Adult Spinal
  • Myelopathic Muscular Atrophy
  • Myelopathic Muscular Atrophy, Progressive
  • Oculopharyngeal Spinal Muscular Atrophy
  • Progressive Muscular Atrophy
  • Progressive Myelopathic Muscular Atrophy
  • Progressive Proximal Myelopathic Muscular Atrophy
  • Proximal Myelopathic Muscular Atrophy, Progressive
  • Scapuloperoneal Form of Spinal Muscular Atrophy
  • Scapuloperoneal Spinal Muscular Atrophy
  • Spinal Muscular Atrophy, Distal
  • Spinal Muscular Atrophy, Oculopharyngeal
  • Spinal Muscular Atrophy, Scapuloperoneal
  • Spinal Muscular Atrophy, Scapuloperoneal Form
  • Adult Onset Spinal Muscular Atrophy
  • Atrophies, Progressive Muscular
  • Atrophy, Myelopathic Muscular
  • Atrophy, Progressive Muscular
  • Bulbospinal Neuronopathies
  • Hereditary Motor Neuronopathies
  • Motor Neuronopathies, Hereditary
  • Motor Neuronopathy, Hereditary
  • Muscular Atrophies, Progressive
  • Muscular Atrophy, Myelopathic
  • Muscular Atrophy, Progressive
  • Neuronopathies, Bulbospinal
  • Neuronopathies, Hereditary Motor
  • Neuronopathy, Bulbospinal
  • Neuronopathy, Hereditary Motor
  • Progressive Muscular Atrophies

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

MUSCULAR ATROPHY, SPINAL, INFANTILE see SPINAL MUSCULAR ATROPHIES OF CHILDHOOD is also available

MeSH Record

History Note

1988

MeSH Record

Previous Indexing

  • Muscular Atrophy (1966-1987)
  • Spinal Cord Diseases (1966-1987)

MeSH Hierarchy

Tree Numbers

  1. C10w.228w.854w.468w
  2. C10w.574w.562w.500w
  3. C10w.668w.467w.500w

MeSH Record

NLM Classification

WE 550

AMA Style

References

  1. National Library of Medicine. Spinal Muscular Atrophy. Medical Subject Headings (MeSH). 2026. Unique ID D009134. http://id.nlm.nih.gov/mesh/2026/D009134
  2. Spinal Muscular Atrophy. In: Wikipedia. https://en.wikipedia.org/wiki/Spinal_muscular_atrophies
  3. Spinal Muscular Atrophy. In: Wikidata. https://www.wikidata.org/wiki/Q7577466