Chemicals and Drugs

Sphingolipid Activator Proteins

A family of glycoprotein cofactors that are required for the efficient catabolization of SPHINGOLIPIDS by specific acid hydrolases such as GLUCOSYLCERAMIDASE; GALACTOCEREBROSIDASE; BETA-N-ACETYLHEXOSAMINIDASE; and CEREBROSIDE-SULFATASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of glycoprotein cofactors that are required for the efficient catabolization of SPHINGOLIPIDS by specific acid hydrolases such as GLUCOSYLCERAMIDASE; GALACTOCEREBROSIDASE; BETA-N-ACETYLHEXOSAMINIDASE; and CEREBROSIDE-SULFATASE.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

8 entry terms
  • Cerebroside Sulfate Activator Protein
  • G(M1) Activator Protein
  • G(M1) Ganglioside Activating Factor
  • GM1 Activator Protein
  • Ganglioside Degradation Activator Protein
  • Ganglioside Hydrolysis Activator Proteins
  • Hexosaminidase A Activating Protein
  • Hexosaminidase Activating Factor

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2005(1977)

MeSH Record

Previous Indexing

  • Glycoproteins (1977-2004)

MeSH Hierarchy

Tree Number

  1. D08.211w.790

AMA Style

References

  1. National Library of Medicine. Sphingolipid Activator Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D049128. http://id.nlm.nih.gov/mesh/2026/D049128
  2. Sphingolipid Activator Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q78128492