Chemicals and Drugs

Spermidine Synthase

An enzyme that catalyzes the transfer of the propylamine moiety from 5'-deoxy-5'-S-(3-methylthiopropylamine)sulfonium adenosine to putrescine in the biosynthesis of spermidine. The enzyme has a molecular weight of approximately 73,000 kDa and is composed of two subunits of equal size.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme that catalyzes the transfer of the propylamine moiety from 5'-deoxy-5'-S-(3-methylthiopropylamine)sulfonium adenosine to putrescine in the biosynthesis of spermidine. The enzyme has a molecular weight of approximately 73,000 kDa and is composed of two subunits of equal size.

MeSH Record

Classification

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MeSH Record

Synonyms

8 entry terms
  • Aminopropyltransferase
  • Propylamine Transferase
  • Putrescine Aminopropyltransferase
  • Spermidine Synthetase
  • Aminopropyltransferase, Putrescine
  • Synthase, Spermidine
  • Synthetase, Spermidine
  • Transferase, Propylamine

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

do not confuse with SPERMINE SYNTHASE

MeSH Record

History Note

97; was PROPYLAMINE TRANSFERASE 1975-96 (see under TRANSFERASES 1975-90); SPERMIDINE SYNTHASE was see PROPYLAMINE TRANSFERASE 1975-96

MeSH Record

Previous Indexing

  • Propylamines (1972-1974)
  • Spermidine (1972-1974)
  • Transferases (1972-1974)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Spermidine Synthase. Medical Subject Headings (MeSH). 2026. Unique ID D011436. http://id.nlm.nih.gov/mesh/2026/D011436
  2. Spermidine Synthase. In: Wikipedia. https://en.wikipedia.org/wiki/Spermidine_synthase
  3. Spermidine Synthase. In: Wikidata. https://www.wikidata.org/wiki/Q3966525