Structured Summary
Abstract
An antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems.
Chemical Identity
Chemical Information
- Molecular Formula
- C13H19N3O5S2
- Molecular Weight
- 361.4 g/mol
- CAS Registry No.
- 1404-64-4
- IUPAC Name
- (E)-N-[(2S)-1-hydroxy-3-[(R)-methylsulfanylmethylsulfinyl]propan-2-yl]-3-(6-methyl-2,4-dioxo-1H-pyrimidin-5-yl)prop-2-enamide
- InChIKey
- XKLZIVIOZDNKEQ-CLQLPEFOSA-N
- SMILES
- CC1=C(C(=O)NC(=O)N1)/C=C/C(=O)N[C@@H](CO)C[S@@](=O)CSC
- MeSH Unique ID
- D013033
- Source
- PubChem CID 9543443
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Aspects Covered
26 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
an antineoplastic antibiotic
MeSH Record
History Note
91(75); was see under ANTIBIOTICS, ANTINEOPLASTIC 1975-90
MeSH Record
Previous Indexing
- Antibiotics (1974)
- Antibiotics, Antineoplastic (1974)
- Ribonucleosides (1974)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Sparsomycin. Medical Subject Headings (MeSH). 2026. Unique ID D013033. http://id.nlm.nih.gov/mesh/2026/D013033
- Sparsomycin. In: Wikipedia. https://en.wikipedia.org/wiki/Sparsomycin
- Sparsomycin. In: Wikidata. https://www.wikidata.org/wiki/Q7573806
- Sparsomycin. In: PubChem Compound. CID 9543443. https://pubchem.ncbi.nlm.nih.gov/compound/9543443