Chemicals and Drugs

Somatostatin Receptors

Cell surface proteins that bind somatostatin and trigger intracellular changes which influence the behavior of cells. Somatostatin is a hypothalamic hormone, a pancreatic hormone, and a central and peripheral neurotransmitter. Activated somatostatin receptors on pituitary cells inhibit the release of growth hormone; those on endocrine and gastrointestinal cells regulate the absorption and utilization of nutrients; and those on neurons mediate somatostatin's role as a neurotransmitter.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Cell surface proteins that bind somatostatin and trigger intracellular changes which influence the behavior of cells. Somatostatin is a hypothalamic hormone, a pancreatic hormone, and a central and peripheral neurotransmitter. Activated somatostatin receptors on pituitary cells inhibit the release of growth hormone; those on endocrine and gastrointestinal cells regulate the absorption and utilization of nutrients; and those on neurons mediate somatostatin's role as a neurotransmitter.

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Synonyms

6 entry terms
  • Receptors, SRIH
  • Receptors, Somatostatin
  • Receptors, Somatotropin Release Inhibiting Hormone
  • SRIH Receptors
  • Somatostatin Receptor
  • Receptor, Somatostatin

MeSH Record

Aspects Covered

19 allowable subheadings

Indexed with the subheadings administration & dosage, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

93; was SOMATOSTATIN RECEPTOR (NM) 1981-92

MeSH Record

Previous Indexing

  • Receptors, Endogenous Substances (1981-1986)
  • Receptors, Neurohumor (1986-1992)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.750w.695w.850w
  2. D12.776w.543w.750w.720w.600w.760w
  3. D12.776w.543w.750w.750w.555w.760w
  4. D12.776w.543w.750w.750w.580.720w
  5. D12.776w.543w.750w.750w.700.800w

AMA Style

References

  1. National Library of Medicine. Somatostatin Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D017481. http://id.nlm.nih.gov/mesh/2026/D017481
  2. Somatostatin Receptors. In: Wikipedia. https://en.wikipedia.org/wiki/Somatostatin_receptor
  3. Somatostatin Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q2067077