Chemicals and Drugs

Sodium Potassium Chloride Symporter Inhibitors

Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Agents that inhibit SODIUM-POTASSIUM-CHLORIDE SYMPORTERS which are concentrated in the thick ascending limb at the junction of the LOOP OF HENLE and KIDNEY TUBULES, DISTAL. They act as DIURETICS. Excess use is associated with HYPOKALEMIA and HYPERGLYCEMIA.

MeSH Record

Classification

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MeSH Record

Synonyms

14 entry terms
  • Bumetanide Sensitive Na-K-Cl-Transporter Inhibitors
  • Na-K-CL Symporter Inhibitors
  • Sodium Potassium Chloride Cotransporter Inhibitors
  • Bumetanide Sensitive Na K Cl Transporter Inhibitors
  • Inhibitors, Na-K-CL Symporter
  • Na K CL Symporter Inhibitors
  • Symporter Inhibitors, Na-K-CL
  • High Ceiling Diuretics
  • Loop Diuretic
  • Loop Diuretics
  • Ceiling Diuretics, High
  • Diuretic, Loop
  • Diuretics, High Ceiling
  • Diuretics, Loop

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2006

MeSH Record

Previous Indexing

  • Sodium-Potassium-Chloride Symporters (2002-2005)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Sodium Potassium Chloride Symporter Inhibitors. Medical Subject Headings (MeSH). 2026. Unique ID D049994. http://id.nlm.nih.gov/mesh/2026/D049994
  2. Sodium Potassium Chloride Symporter Inhibitors. In: Wikidata. https://www.wikidata.org/wiki/Q50430324