Structured Summary
Abstract
A sodium-hydrogen antiporter expressed primarily by EPITHELIAL CELLS in the kidneys, it localizes to the apical membrane of the PROXIMAL KIDNEY TUBULE, where it functions in sodium and water reabsorption and possibly calcium homeostasis. It also is expressed in heart, brain, and lung tissues and is resistant to AMILORIDE inhibition.
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Classification
Broader headings
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MeSH Record
Synonyms
6 entry terms
- NHE-3 Protein
- Na(+)-H(+) Exchanger 3
- SLC9A3 Protein
- Solute Carrier Family 9 Member 3
- NHE 3 Protein
- Sodium Hydrogen Exchanger 3
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2018 (1994)
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AMA Style
References
- National Library of Medicine. Sodium-Hydrogen Exchanger 3. Medical Subject Headings (MeSH). 2026. Unique ID D000074083. http://id.nlm.nih.gov/mesh/2026/D000074083
- Sodium-Hydrogen Exchanger 3. In: Wikidata. https://www.wikidata.org/wiki/Q21107999