Diseases

Smoldering Multiple Myeloma

An asymptomatic and slow-growing PLASMA CELL dyscrasia characterized by presence of MYELOMA PROTEINS and clonal bone marrow plasma cells without end-organ damage (e.g., renal impairment). It is distinguished from MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE by a much higher risk of progression to symptomatic MULTIPLE MYELOMA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An asymptomatic and slow-growing PLASMA CELL dyscrasia characterized by presence of MYELOMA PROTEINS and clonal bone marrow plasma cells without end-organ damage (e.g., renal impairment). It is distinguished from MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE by a much higher risk of progression to symptomatic MULTIPLE MYELOMA.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

9 entry terms
  • Asymptomatic Multiple Myeloma
  • Smoldering Myeloma
  • Asymptomatic Multiple Myelomas
  • Multiple Myeloma, Asymptomatic
  • Multiple Myeloma, Smoldering
  • Multiple Myelomas, Asymptomatic
  • Myeloma, Smoldering
  • Smoldering Multiple Myelomas
  • Smoldering Myelomas

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2018

MeSH Record

Previous Indexing

  • Multiple Myeloma (1980-2017)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Smoldering Multiple Myeloma. Medical Subject Headings (MeSH). 2026. Unique ID D000075122. http://id.nlm.nih.gov/mesh/2026/D000075122
  2. Smoldering Multiple Myeloma. In: Wikipedia. https://en.wikipedia.org/wiki/Smouldering_myeloma
  3. Smoldering Multiple Myeloma. In: Wikidata. https://www.wikidata.org/wiki/Q17146000