Chemicals and Drugs

Smallpox Vaccine

A VACCINIA VIRUS vaccine used for immunization against SMALLPOX. It is now recommended only for laboratory workers exposed to SMALLPOX VIRUS. Certain countries continue to vaccinate those in the military service. Rare complications most often associated with older generation smallpox vaccines include VACCINIA, secondary bacterial infections, and ENCEPHALOMYELITIS. Because MONKEYPOX VIRUS and SMALLPOX VIRUS are both ORTHOPOXVIRUS and are closely related smallpox vaccines provide effective CROSS-PROTECTION against MPOX, MONKEYPOX (https://www.cdc.gov/poxvirus/monkeypox/clinicians/smallpox-vaccine.html).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A VACCINIA VIRUS vaccine used for immunization against SMALLPOX. It is now recommended only for laboratory workers exposed to SMALLPOX VIRUS. Certain countries continue to vaccinate those in the military service. Rare complications most often associated with older generation smallpox vaccines include VACCINIA, secondary bacterial infections, and ENCEPHALOMYELITIS. Because MONKEYPOX VIRUS and SMALLPOX VIRUS are both ORTHOPOXVIRUS and are closely related smallpox vaccines provide effective CROSS-PROTECTION against MPOX, MONKEYPOX (https://www.cdc.gov/poxvirus/monkeypox/clinicians/smallpox-vaccine.html).

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Synonyms

15 entry terms
  • Small Pox Vaccine
  • Vaccine, Small Pox
  • Vaccine, Smallpox
  • Monkey Pox Vaccine
  • Monkeypox Vaccine
  • Monkeypox and Smallpox Vaccine
  • Mpox Vaccine
  • Mpox and Smallpox Vaccine
  • Smallpox and Monkeypox Vaccine
  • Smallpox and Mpox Vaccine
  • Vaccinia Vaccine
  • Vaccine, Monkey Pox
  • Vaccine, Monkeypox
  • Vaccine, Mpox
  • Vaccine, Vaccinia

MeSH Record

Aspects Covered

26 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

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References

  1. National Library of Medicine. Smallpox Vaccine. Medical Subject Headings (MeSH). 2026. Unique ID D012900. http://id.nlm.nih.gov/mesh/2026/D012900
  2. Smallpox Vaccine. In: Wikipedia. https://en.wikipedia.org/wiki/Smallpox_vaccine
  3. Smallpox Vaccine. In: Wikidata. https://www.wikidata.org/wiki/Q1037810