Diseases

Sjogren's Syndrome

Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Chronic inflammatory and autoimmune disease in which the salivary and lacrimal glands undergo progressive destruction by lymphocytes and plasma cells resulting in decreased production of saliva and tears. The primary form, often called sicca syndrome, involves both KERATOCONJUNCTIVITIS SICCA and XEROSTOMIA. The secondary form includes, in addition, the presence of a connective tissue disease, usually rheumatoid arthritis.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

5 entry terms
  • Sjogren Syndrome
  • Sjogrens Syndrome
  • Syndrome, Sjogren's
  • Sicca Syndrome
  • Syndrome, Sicca

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

a form of rheum arthritis; do not confuse with SJOGREN-LARSSON SYNDROME, a form of ichthyosis; in titles & translations, use diacrit: Sjogren

MeSH Hierarchy

Tree Numbers

  1. C05w.550w.114w.154w.774w
  2. C05w.799w.114w.774w
  3. C07.465w.815w.929w.669w
  4. C11w.496.260.719w
  5. C17.300w.775w.099w.774w
  6. C20w.111w.199w.774w

MeSH Record

NLM Classification

WE 346

AMA Style

References

  1. National Library of Medicine. Sjogren's Syndrome. Medical Subject Headings (MeSH). 2026. Unique ID D012859. http://id.nlm.nih.gov/mesh/2026/D012859
  2. Sjogren's Syndrome. In: Wikipedia. https://en.wikipedia.org/wiki/Sj%C3%B6gren%27s_disease
  3. Sjogren's Syndrome. In: Wikidata. https://www.wikidata.org/wiki/Q335555