Chemicals and Drugs

Site-Specific DNA-Methyltransferase (Adenine-Specific)

An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyzes the methylation of DNA adenine in the presence of S-adenosyl-L-methionine to form DNA containing 6-methylaminopurine and S-adenosyl-L-homocysteine. EC 2.1.1.72.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An enzyme responsible for producing a species-characteristic methylation pattern on adenine residues in a specific short base sequence in the host cell DNA. The enzyme catalyzes the methylation of DNA adenine in the presence of S-adenosyl-L-methionine to form DNA containing 6-methylaminopurine and S-adenosyl-L-homocysteine. EC 2.1.1.72.

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Classification

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MeSH Record

Synonyms

9 entry terms
  • DNA Modification Methylases (Adenine-Specific)
  • DNA Modification Methylases Adenine Specific
  • DNA-Adenine Methylases
  • Modification Methylases (Adenine Specific)
  • Modification Methylases (Adenine-Specific)
  • Site Specific Methyltransferases (Adenine Specific)
  • Site-Specific Methyltransferases (Adenine-Specific)
  • DNA Adenine Methylases
  • Methylases, DNA-Adenine

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

98(89)

MeSH Record

Previous Indexing

  • Methyltransferases (1971-1988)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Site-Specific DNA-Methyltransferase (Adenine-Specific). Medical Subject Headings (MeSH). 2026. Unique ID D015265. http://id.nlm.nih.gov/mesh/2026/D015265
  2. Site-Specific DNA-Methyltransferase (Adenine-Specific). In: Wikipedia. https://en.wikipedia.org/wiki/DNA_adenine_methylase
  3. Site-Specific DNA-Methyltransferase (Adenine-Specific). In: Wikidata. https://www.wikidata.org/wiki/Q4463683