Chemicals and Drugs

Serum-Glucocorticoid Regulated Kinases

Serine-threonine-protein kinases that regulates a variety of ION CHANNELS and MEMBRANE TRANSPORT PROTEINS, as well as cellular processes that include neuronal excitability, CELL PROLIFERATION; CELL SURVIVAL; and APOPTOSIS. They also have important roles in the cellular stress response (STRESS, PHYSIOLOGICAL), renal sodium retention and potassium elimination.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Serine-threonine-protein kinases that regulates a variety of ION CHANNELS and MEMBRANE TRANSPORT PROTEINS, as well as cellular processes that include neuronal excitability, CELL PROLIFERATION; CELL SURVIVAL; and APOPTOSIS. They also have important roles in the cellular stress response (STRESS, PHYSIOLOGICAL), renal sodium retention and potassium elimination.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

4 entry terms
  • SGK Kinase
  • SGK Kinases
  • Serum and Glucocorticoid-Regulated Kinase
  • Serum-Glucocorticoid Regulated Kinase

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2026 (1993); use SERUM-GLUCOCORTICOID REGULATED KINASE (NM) 1993-2025

MeSH Hierarchy

Tree Numbers

  1. D08.811w.913w.696w.620.682w.700w.900
  2. D12.776w.460.644
  3. D12.776w.476.563w.900

AMA Style

References

  1. National Library of Medicine. Serum-Glucocorticoid Regulated Kinases. Medical Subject Headings (MeSH). 2026. Unique ID D000099184. http://id.nlm.nih.gov/mesh/2026/D000099184
  2. Serum-Glucocorticoid Regulated Kinases. In: Wikidata. https://www.wikidata.org/wiki/Q25376909