Chemicals and Drugs

Serotonin 5-HT2C Receptor

A serotonin receptor subtype found primarily in the CENTRAL NERVOUS SYSTEM and the CHOROID PLEXUS. This receptor subtype is believed to mediate the anorectic action of SEROTONIN, while selective antagonists of the 5-HT2C receptor appear to induce ANXIETY. Several isoforms of this receptor subtype exist, due to adenine deaminase editing of the receptor mRNA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A serotonin receptor subtype found primarily in the CENTRAL NERVOUS SYSTEM and the CHOROID PLEXUS. This receptor subtype is believed to mediate the anorectic action of SEROTONIN, while selective antagonists of the 5-HT2C receptor appear to induce ANXIETY. Several isoforms of this receptor subtype exist, due to adenine deaminase editing of the receptor mRNA.

MeSH Record

Classification

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MeSH Record

Synonyms

13 entry terms
  • 5-HT(2C) Receptor
  • 5-HT2C Receptor
  • 5-Hydroxytryptamine Type 2C Receptor
  • 5-Hydroxytryptamine Type 2C Receptors
  • Receptor, 5-Hydroxytryptamine Type 2C
  • Receptor, Serotonin, 5-HT2C
  • Serotonin 2C Receptor
  • 5 HT2C Receptor
  • 5 Hydroxytryptamine Type 2C Receptor
  • 5 Hydroxytryptamine Type 2C Receptors
  • Receptor, 5 Hydroxytryptamine Type 2C
  • Receptor, 5-HT2C
  • Receptor, Serotonin 2C

MeSH Record

Aspects Covered

17 allowable subheadings

Indexed with the subheadings administration & dosage, analysis, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2004; use RECEPTOR, SEROTONIN, 5-HT2C (NM) 1994-2003

MeSH Record

Previous Indexing

  • Receptors, Serotonin (1994-2003)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Serotonin 5-HT2C Receptor. Medical Subject Headings (MeSH). 2026. Unique ID D044405. http://id.nlm.nih.gov/mesh/2026/D044405
  2. Serotonin 5-HT2C Receptor. In: Wikidata. https://www.wikidata.org/wiki/Q24781580