Chemicals and Drugs

Serine C-Palmitoyltransferase

A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL COENZYME A to 3-dehydro-D-sphinganine. The enzyme consists of two different subunits.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A key enzyme in SPHINGOLIPIDS biosynthesis, this enzyme catalyzes the pyridoxal-5'-phosphate-dependent condensation of L-SERINE and PALMITOYL COENZYME A to 3-dehydro-D-sphinganine. The enzyme consists of two different subunits.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

17 entry terms
  • Palmitoyl-CoA-L-Serine C-Palmitoyltransferase (Decarboxylating)
  • Palmitoyl-Coenzyme A-L-Serine C-Palmitoyltransferase (Decarboxylating)
  • Serine Palmitoyltransferase
  • C-Palmitoyltransferase, Serine
  • Palmitoyltransferase, Serine
  • Serine C Palmitoyltransferase
  • Long Chain Base Biosynthesis Protein 1
  • Long Chain Base Biosynthesis Protein 2
  • Serine Palmitoyltransferase 1
  • Serine Palmitoyltransferase 2
  • Serine Palmitoyltransferase, Long Chain Base Subunit 1
  • Serine Palmitoyltransferase, Long Chain Base Subunit 2
  • Serine-Palmitoyl-CoA Transferase 2
  • Palmitoyltransferase 1, Serine
  • Palmitoyltransferase 2, Serine
  • Serine Palmitoyl CoA Transferase 2
  • Transferase 2, Serine-Palmitoyl-CoA

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1984)

MeSH Record

Previous Indexing

  • Acyltransferases (1984-2005)

MeSH Hierarchy

Tree Number

  1. D08.811w.913w.050w.668w

AMA Style

References

  1. National Library of Medicine. Serine C-Palmitoyltransferase. Medical Subject Headings (MeSH). 2026. Unique ID D051102. http://id.nlm.nih.gov/mesh/2026/D051102
  2. Serine C-Palmitoyltransferase. In: Wikipedia. https://en.wikipedia.org/wiki/Serine_C-palmitoyltransferase
  3. Serine C-Palmitoyltransferase. In: Wikidata. https://www.wikidata.org/wiki/Q3511352