Chemicals and Drugs

Septins

A family of GTP-binding proteins that were initially identified in YEASTS where they were shown to initiate the process of septation and bud formation. Septins form into hetero-oligomeric complexes that are comprised of several distinct septin subunits. These complexes can act as cytoskeletal elements that play important roles in CYTOKINESIS, cytoskeletal reorganization, BIOLOGICAL TRANSPORT, and membrane dynamics.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A family of GTP-binding proteins that were initially identified in YEASTS where they were shown to initiate the process of septation and bud formation. Septins form into hetero-oligomeric complexes that are comprised of several distinct septin subunits. These complexes can act as cytoskeletal elements that play important roles in CYTOKINESIS, cytoskeletal reorganization, BIOLOGICAL TRANSPORT, and membrane dynamics.

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

1 entry terms
  • Septin

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2011

MeSH Hierarchy

Tree Numbers

  1. D08.811w.277w.040w.330.300.700w
  2. D12.776w.157w.325.757w
  3. D12.776w.220.932w
  4. D12.776w.476.338.700w

AMA Style

References

  1. National Library of Medicine. Septins. Medical Subject Headings (MeSH). 2026. Unique ID D058112. http://id.nlm.nih.gov/mesh/2026/D058112
  2. Septins. In: Wikipedia. https://en.wikipedia.org/wiki/Septin
  3. Septins. In: Wikidata. https://www.wikidata.org/wiki/Q24720212