Chemicals and Drugs

Senotherapeutics

Chemical agents which induce the removal (by apoptotic or non-apoptotic cell death) or immune-mediated clearance of senescent cells, or the neutralization of the detrimental effects of the SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Chemical agents which induce the removal (by apoptotic or non-apoptotic cell death) or immune-mediated clearance of senescent cells, or the neutralization of the detrimental effects of the SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

20 entry terms
  • Seno-Therapeutic Agents
  • Senotherapeutic Agents
  • Agents, Seno-Therapeutic
  • Agents, Senotherapeutic
  • Seno Therapeutic Agents
  • Geroprotectors
  • Senolytic Agents
  • Senolytics
  • Senomorphic Agents
  • Senomorphics
  • Senoptosis Inducers
  • Senoptotic Agents
  • Senoptotics
  • Senostatic Agents
  • Senostatics
  • Agents, Senolytic
  • Agents, Senomorphic
  • Agents, Senoptotic
  • Agents, Senostatic
  • Inducers, Senoptosis

MeSH Record

Aspects Covered

22 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2022

MeSH Record

Previous Indexing

  • Cellular Senescence (2016-2021)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Senotherapeutics. Medical Subject Headings (MeSH). 2026. Unique ID D000089322. http://id.nlm.nih.gov/mesh/2026/D000089322
  2. Senotherapeutics. In: Wikipedia. https://en.wikipedia.org/wiki/Senolytic
  3. Senotherapeutics. In: Wikidata. https://www.wikidata.org/wiki/Q19587281