Structured Summary
Abstract
4-Methyl derivative of LOMUSTINE; (CCNU). An antineoplastic agent which functions as an alkylating agent.
Chemical Identity
Chemical Information
- Molecular Formula
- C10H18ClN3O2
- Molecular Weight
- 247.72 g/mol
- CAS Registry No.
- 13909-09-6
- IUPAC Name
- 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea
- InChIKey
- FVLVBPDQNARYJU-UHFFFAOYSA-N
- SMILES
- CC1CCC(CC1)NC(=O)N(CCCl)N=O
- MeSH Unique ID
- D012673
- Source
- PubChem CID 5198
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
8 entry terms
- Me-CCNU
- MeCCNU
- Methyl-CCNU
- Me CCNU
- Methyl CCNU
- NSC-95441
- NSC 95441
- NSC95441
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
91(75); was see under NITROSOUREA COMPOUNDS 1975-90
MeSH Record
Previous Indexing
- Cyclohexanes (1966-1974)
- Nitroso Compounds (1966-1972)
- Nitrosourea Compounds (1973-1974)
- Urea (1966-1972)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Semustine. Medical Subject Headings (MeSH). 2026. Unique ID D012673. http://id.nlm.nih.gov/mesh/2026/D012673
- Semustine. In: Wikipedia. https://en.wikipedia.org/wiki/Semustine
- Semustine. In: Wikidata. https://www.wikidata.org/wiki/Q1230937
- Semustine. In: PubChem Compound. CID 5198. https://pubchem.ncbi.nlm.nih.gov/compound/5198