Diseases

Seminoma

A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A radiosensitive, malignant neoplasm of the testis, thought to be derived from primordial germ cells of the sexually undifferentiated embryonic gonad. There are three variants: classical (typical), the most common type; anaplastic; and spermatocytic. The classical seminoma is composed of fairly well differentiated sheets or cords of uniform polygonal or round cells (seminoma cells), each cell having abundant clear cytoplasm, distinct cell membranes, a centrally placed round nucleus, and one or more nucleoli. In the female, a grossly and histologically identical neoplasm, known as dysgerminoma, occurs. (Dorland, 27th ed)

MeSH Record

Classification

Broader headings

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MeSH Record

Synonyms

1 entry terms
  • Seminomas

MeSH Record

Aspects Covered

39 allowable subheadings

Indexed with the subheadings blood, blood supply, cerebrospinal fluid, chemically induced, chemistry, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, secondary, surgery, therapy, ultrastructure, urine, veterinary, virology.

MeSH Record

Indexing Annotation

coordinate with TESTICULAR NEOPLASMS

MeSH Record

History Note

94; was see DYSGERMINOMA 1979-93

MeSH Record

Previous Indexing

  • Dysgerminoma (1966-1993)

MeSH Hierarchy

Tree Number

  1. C04w.557.465.330w.800w

AMA Style

References

  1. National Library of Medicine. Seminoma. Medical Subject Headings (MeSH). 2026. Unique ID D018239. http://id.nlm.nih.gov/mesh/2026/D018239
  2. Seminoma. In: Wikipedia. https://en.wikipedia.org/wiki/Seminoma
  3. Seminoma. In: Wikidata. https://www.wikidata.org/wiki/Q1786953