Chemicals and Drugs

Secretory Immunoglobulin A

The principle immunoglobulin in exocrine secretions such as milk, respiratory and intestinal mucin, saliva and tears. The complete molecule (around 400 kD) is composed of two four-chain units of IMMUNOGLOBULIN A, one SECRETORY COMPONENT and one J chain (IMMUNOGLOBULIN J-CHAINS).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

The principle immunoglobulin in exocrine secretions such as milk, respiratory and intestinal mucin, saliva and tears. The complete molecule (around 400 kD) is composed of two four-chain units of IMMUNOGLOBULIN A, one SECRETORY COMPONENT and one J chain (IMMUNOGLOBULIN J-CHAINS).

MeSH Record

Classification

Broader headings

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Drug Class

Pharmacological Action

MeSH Record

See Also

MeSH Record

Synonyms

8 entry terms
  • IgA, Exocrine
  • IgA, Secretory
  • Immunoglobulin A, Secretory
  • SIgA
  • Secretory IgA
  • Exocrine IgA
  • Colostral IgA
  • IgA, Colostral

MeSH Record

Aspects Covered

23 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, biosynthesis, blood, cerebrospinal fluid, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacology, physiology, poisoning, radiation effects, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

Indexing Annotation

salivary immunoglobulin A: index IGA, SECRETORY + SALIVA/ immunol; immunoglobulin A in tears: index IGA, SECRETORY + TEARS/ immunol; /defic = IMMUNOGLOBULIN A, SECRETORY + IGA DEFICIENCY

MeSH Record

History Note

2002(1976)

MeSH Record

Previous Indexing

  • Colostrum (1973-1975)
  • IgA (1973-1975)
  • Immunoglobulin Fragments (1973-1975)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Secretory Immunoglobulin A. Medical Subject Headings (MeSH). 2026. Unique ID D007071. http://id.nlm.nih.gov/mesh/2026/D007071
  2. Secretory Immunoglobulin A. In: Wikidata. https://www.wikidata.org/wiki/Q77201340