Diseases

Scleromyxedema

A connective tissue disorder characterized by widespread thickening of SKIN with a cobblestone-like appearance. It is caused by proliferation of FIBROBLASTS and deposition of MUCIN in the DERMIS in the absence of thyroid disease. Most scleromyxedema cases are associated with a MONOCLONAL GAMMOPATHY, immunoglobulin IgG-lambda.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A connective tissue disorder characterized by widespread thickening of SKIN with a cobblestone-like appearance. It is caused by proliferation of FIBROBLASTS and deposition of MUCIN in the DERMIS in the absence of thyroid disease. Most scleromyxedema cases are associated with a MONOCLONAL GAMMOPATHY, immunoglobulin IgG-lambda.

MeSH Record

Classification

Broader headings

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MeSH Record

See Also

MeSH Record

Synonyms

4 entry terms
  • Lichen Myxedematosus
  • Papular Mucinosis
  • Mucinosis, Papular
  • Myxedematosus, Lichen

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

History Note

2007

MeSH Record

Previous Indexing

  • Myxedema (1963-2006)

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Scleromyxedema. Medical Subject Headings (MeSH). 2026. Unique ID D053718. http://id.nlm.nih.gov/mesh/2026/D053718
  2. Scleromyxedema. In: Wikipedia. https://en.wikipedia.org/wiki/Papular_mucinosis
  3. Scleromyxedema. In: Wikidata. https://www.wikidata.org/wiki/Q17144875