Chemicals and Drugs

Sarin

An organophosphorus ester compound that produces potent and irreversible inhibition of cholinesterase. It is toxic to the nervous system and is a chemical warfare agent.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

An organophosphorus ester compound that produces potent and irreversible inhibition of cholinesterase. It is toxic to the nervous system and is a chemical warfare agent.

Chemical Identity

Chemical Information

Molecular Formula
C4H10FO2P
Molecular Weight
140.09 g/mol
CAS Registry No.
107-44-8
IUPAC Name
2-[fluoro(methyl)phosphoryl]oxypropane
InChIKey
DYAHQFWOVKZOOW-UHFFFAOYSA-N
SMILES
CC(C)OP(=O)(C)F
MeSH Unique ID
D012524
Source
PubChem CID 7871

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

8 entry terms
  • o-Isopropylmethyl Phosphonofluoridate
  • ortho-Isopropylmethyl Phosphonofluoridate
  • Phosphonofluoridate, o-Isopropylmethyl
  • Phosphonofluoridate, ortho-Isopropylmethyl
  • o Isopropylmethyl Phosphonofluoridate
  • ortho Isopropylmethyl Phosphonofluoridate
  • Sarin Gas
  • Gas, Sarin

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(72); was see under ORGANOPHOSPHORUS COMPOUNDS 1972-90

MeSH Record

Previous Indexing

  • Cholinesterase Inhibitors (1966-1971)
  • Organophosphorus Compounds (1971)

MeSH Hierarchy

Tree Number

  1. D02w.705w.429.750.500w

AMA Style

References

  1. National Library of Medicine. Sarin. Medical Subject Headings (MeSH). 2026. Unique ID D012524. http://id.nlm.nih.gov/mesh/2026/D012524
  2. Sarin. In: Wikipedia. https://en.wikipedia.org/wiki/Sarin
  3. Sarin. In: Wikidata. https://www.wikidata.org/wiki/Q187695
  4. Sarin. In: PubChem Compound. CID 7871. https://pubchem.ncbi.nlm.nih.gov/compound/7871