Chemicals and Drugs

SNARE Proteins

A superfamily of small proteins which are involved in the MEMBRANE FUSION events, intracellular protein trafficking and secretory processes. They share a homologous SNARE motif. The SNARE proteins are divided into subfamilies: QA-SNARES; QB-SNARES; QC-SNARES; and R-SNARES. The formation of a SNARE complex (composed of one each of the four different types SNARE domains (Qa, Qb, Qc, and R)) mediates MEMBRANE FUSION. Following membrane fusion SNARE complexes are dissociated by the NSFs (N-ETHYLMALEIMIDE-SENSITIVE FACTORS), in conjunction with SOLUBLE NSF ATTACHMENT PROTEIN, i.e., SNAPs (no relation to SNAP 25.)

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A superfamily of small proteins which are involved in the MEMBRANE FUSION events, intracellular protein trafficking and secretory processes. They share a homologous SNARE motif. The SNARE proteins are divided into subfamilies: QA-SNARES; QB-SNARES; QC-SNARES; and R-SNARES. The formation of a SNARE complex (composed of one each of the four different types SNARE domains (Qa, Qb, Qc, and R)) mediates MEMBRANE FUSION. Following membrane fusion SNARE complexes are dissociated by the NSFs (N-ETHYLMALEIMIDE-SENSITIVE FACTORS), in conjunction with SOLUBLE NSF ATTACHMENT PROTEIN, i.e., SNAPs (no relation to SNAP 25.)

MeSH Record

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MeSH Record

Synonyms

22 entry terms
  • NSF Attachment Protein Receptor
  • Receptor, SNAP
  • SNAP Receptor
  • SNAP Receptors
  • SNARE
  • SNARE Protein
  • SNAREs
  • Soluble N-ethylmaleimide-Sensitive-Factor Attachment Protein Receptor
  • Protein, SNARE
  • Soluble N ethylmaleimide Sensitive Factor Attachment Protein Receptor
  • Target Membrane SNARE Proteins
  • Target SNARE Proteins
  • Vesicle SNARE Proteins
  • Vesicular SNARE Proteins
  • t-SNARE
  • tSNAREs
  • v-SNARE
  • v-SNAREs
  • SNARE Proteins, Target
  • SNARE Proteins, Vesicle
  • SNARE Proteins, Vesicular
  • v SNAREs

MeSH Record

Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006 (1995)

MeSH Record

Previous Indexing

  • Membrane Proteins (1994-2005)
  • Vesicular Transport Proteins (2004-2005)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.543w.512w.249w
  2. D12.776w.543w.990w.775w

AMA Style

References

  1. National Library of Medicine. SNARE Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D050600. http://id.nlm.nih.gov/mesh/2026/D050600
  2. SNARE Proteins. In: Wikipedia. https://en.wikipedia.org/wiki/SNARE_protein
  3. SNARE Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q279694