Chemicals and Drugs

SMN Complex Proteins

A complex of proteins that assemble the SNRNP CORE PROTEINS into a core structure that surrounds a highly conserved RNA sequence found in SMALL NUCLEAR RNA. They are found localized in the GEMINI OF COILED BODIES and in the CYTOPLASM. The SMN complex is named after the Survival of Motor Neuron Complex Protein 1, which is a critical component of the complex.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A complex of proteins that assemble the SNRNP CORE PROTEINS into a core structure that surrounds a highly conserved RNA sequence found in SMALL NUCLEAR RNA. They are found localized in the GEMINI OF COILED BODIES and in the CYTOPLASM. The SMN complex is named after the Survival of Motor Neuron Complex Protein 1, which is a critical component of the complex.

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Synonyms

30 entry terms
  • Gem-Associated Proteins
  • Gemin Proteins
  • Survival of Motor Neuron Complex Proteins
  • Gem Associated Proteins
  • Component of Gems 4 Protein
  • FAM51A1 Protein
  • Gemin-2 Protein
  • Gemin-4 Protein
  • Gemin-5 Protein
  • Gemin-6 Protein
  • Gemin-7 Protein
  • Gemin-8 Protein
  • Gemin2 Protein
  • Gemin4 Protein
  • Gemin5 Protein
  • Gemin6 Protein
  • Gemin7 Protein
  • Gemin8 Protein
  • SMN Complex
  • Survival of Motor Neuron Complex
  • Survival of Motor Neuron Protein-Interacting Protein 1
  • Gemin 2 Protein
  • Gemin 4 Protein
  • Gemin 5 Protein
  • Gemin 6 Protein
  • Gemin 7 Protein
  • Gemin 8 Protein
  • Protein, Gemin-7
  • Protein, Gemin7
  • Survival of Motor Neuron Protein Interacting Protein 1

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Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2009(1995)

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.725w.875
  2. D12.776w.580w.922
  3. D12.776w.664w.962w.875

AMA Style

References

  1. National Library of Medicine. SMN Complex Proteins. Medical Subject Headings (MeSH). 2026. Unique ID D055532. http://id.nlm.nih.gov/mesh/2026/D055532
  2. SMN Complex Proteins. In: Wikidata. https://www.wikidata.org/wiki/Q78191293