Structured Summary
Abstract
An S100 protein characterized by four helix bundles that form N- and C-terminal EF HAND MOTIFS. It functions as a homodimer and interacts with both intracellular and extracellular signaling proteins. Aberrant S100A4 activity is associated with NEOPLASM METASTASIS; FIBROSIS; and RHEUMATOID ARTHRITIS.
MeSH Record
Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
9 entry terms
- Calvasculin Protein
- Fibroblast-Specific Protein 1
- Metastasin Protein
- Placental Calcium-Binding Protein
- S100A4 Protein
- Calcium-Binding Protein, Placental
- Fibroblast Specific Protein 1
- Placental Calcium Binding Protein
- S100 Calcium Binding Protein A4
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2017
MeSH Record
Previous Indexing
- Calcium-Binding Proteins (1992-2016)
- S100 Proteins (2003-2016)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. S100 Calcium-Binding Protein A4. Medical Subject Headings (MeSH). 2026. Unique ID D000071999. http://id.nlm.nih.gov/mesh/2026/D000071999
- S100 Calcium-Binding Protein A4. In: Wikidata. https://www.wikidata.org/wiki/Q21109469