Structured Summary
Abstract
Semisynthetic derivative of erythromycin. It is concentrated by human phagocytes and is bioactive intracellularly. While the drug is active against a wide spectrum of pathogens, it is particularly effective in the treatment of respiratory and genital tract infections.
Chemical Identity
Chemical Information
- Molecular Formula
- C41H76N2O15
- Molecular Weight
- 837.0 g/mol
- CAS Registry No.
- 80214-83-1
- IUPAC Name
- (3R,4S,5S,6R,7R,9R,10E,11S,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-10-(2-methoxyethoxymethoxyimino)-3,5,7,9,11,13-hexamethyl-oxacyclotetradecan-2-one
- InChIKey
- RXZBMPWDPOLZGW-XMRMVWPWSA-N
- SMILES
- CC[C@@H]1[C@@]([C@@H]([C@H](/C(=N/OCOCCOC)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O
- MeSH Unique ID
- D015575
- Source
- PubChem CID 6915744
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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Drug Class
Pharmacological Action
MeSH Record
Synonyms
30 entry terms
- Biaxsig
- Claramid
- Infectoroxit
- MTW-Roxithromycin
- Macrosil
- RU 28965
- RU 965
- RU-28965
- RU-965
- Rotesan
- Rotramin
- Roxi 1A Pharma
- Roxi Basics
- Roxi TAD
- Roxi-Puren
- Roxi-Q
- Roxi-Wolff
- Roxi-paed 1A Pharma
- Roxi-saar
- Roxibeta
- Roxigamma
- Roxigrün
- Roxihexal
- Roxithro-Lich
- Rulid
- Rulide
- roxi von ct
- roxidura
- RU28965
- RU965
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
90; was see LEUCOMYCINS 1981-89
MeSH Record
Previous Indexing
- Leucomycins (1981-1989)
MeSH Hierarchy
Tree Number
MeSH Record
NLM Classification
QV 350.5.E7
AMA Style
References
- National Library of Medicine. Roxithromycin. Medical Subject Headings (MeSH). 2026. Unique ID D015575. http://id.nlm.nih.gov/mesh/2026/D015575
- Roxithromycin. In: Wikipedia. https://en.wikipedia.org/wiki/Roxithromycin
- Roxithromycin. In: Wikidata. https://www.wikidata.org/wiki/Q424037
- Roxithromycin. In: PubChem Compound. CID 6915744. https://pubchem.ncbi.nlm.nih.gov/compound/6915744