Chemicals and Drugs

Rotaxanes

Complex compounds in which a dumbbell shaped molecule is encircled by a macrocycle. They are named after rota (wheel) and axis (axle). Notation with a prefix is used to indicate the number of interlocked components. They have potential use in NANOTECHNOLOGY. Rotaxanes have been made with CYCLODEXTRINS and CYCLIC ETHERS.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Complex compounds in which a dumbbell shaped molecule is encircled by a macrocycle. They are named after rota (wheel) and axis (axle). Notation with a prefix is used to indicate the number of interlocked components. They have potential use in NANOTECHNOLOGY. Rotaxanes have been made with CYCLODEXTRINS and CYCLIC ETHERS.

MeSH Record

Classification

Broader headings

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See Also

MeSH Record

Synonyms

4 entry terms
  • Rotaxane
  • Polyrotaxanes
  • Pseudorotaxane
  • Pseudorotaxanes

MeSH Record

Aspects Covered

24 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

coord with specific Cat D chemical structure term if pertinent; TAXANES is also available

MeSH Record

History Note

2004

MeSH Hierarchy

Tree Number

  1. D02w.825w

AMA Style

References

  1. National Library of Medicine. Rotaxanes. Medical Subject Headings (MeSH). 2026. Unique ID D043862. http://id.nlm.nih.gov/mesh/2026/D043862
  2. Rotaxanes. In: Wikipedia. https://en.wikipedia.org/wiki/Rotaxane
  3. Rotaxanes. In: Wikidata. https://www.wikidata.org/wiki/Q901292