Chemicals and Drugs

Rivastigmine

A carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON DISEASE.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment of DEMENTIA in ALZHEIMER DISEASE and PARKINSON DISEASE.

Chemical Identity

Chemical Information

Molecular Formula
C14H22N2O2
Molecular Weight
250.34 g/mol
CAS Registry No.
123441-03-2
IUPAC Name
[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate
InChIKey
XSVMFMHYUFZWBK-NSHDSACASA-N
SMILES
CCN(C)C(=O)OC1=CC=CC(=C1)[C@H](C)N(C)C
MeSH Unique ID
D000068836
Source
PubChem CID 77991

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

13 entry terms
  • (S)-N-Ethyl-3-((1-dimethyl-amino)ethyl)-N-methylphenylcarbamate
  • ENA 713
  • ENA-713
  • Exelon
  • Rivastigmine Hydrogen Tartrate
  • RivastigmineTartrate
  • SDZ ENA 713
  • 713, ENA
  • 713, SDZ ENA
  • ENA 713, SDZ
  • ENA713
  • Hydrogen Tartrate, Rivastigmine
  • Tartrate, Rivastigmine Hydrogen

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2016 (1992)

MeSH Hierarchy

Tree Number

AMA Style

References

  1. National Library of Medicine. Rivastigmine. Medical Subject Headings (MeSH). 2026. Unique ID D000068836. http://id.nlm.nih.gov/mesh/2026/D000068836
  2. Rivastigmine. In: Wikipedia. https://en.wikipedia.org/wiki/Rivastigmine
  3. Rivastigmine. In: Wikidata. https://www.wikidata.org/wiki/Q411887
  4. Rivastigmine. In: PubChem Compound. CID 77991. https://pubchem.ncbi.nlm.nih.gov/compound/77991