Chemicals and Drugs

Risperidone

A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A selective blocker of DOPAMINE D2 RECEPTORS and SEROTONIN 5-HT2 RECEPTORS that acts as an atypical antipsychotic agent. It has been shown to improve both positive and negative symptoms in the treatment of SCHIZOPHRENIA.

Chemical Identity

Chemical Information

Molecular Formula
C23H27FN4O2
Molecular Weight
410.5 g/mol
CAS Registry No.
106266-06-2
IUPAC Name
3-[2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl]-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one
InChIKey
RAPZEAPATHNIPO-UHFFFAOYSA-N
SMILES
CC1=C(C(=O)N2CCCCC2=N1)CCN3CCC(CC3)C4=NOC5=C4C=CC(=C5)F
MeSH Unique ID
D018967
Source
PubChem CID 5073

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • R-64,766
  • R-64766
  • Risperdal Consta
  • Risperidal
  • Consta, Risperdal
  • R 64,766
  • R 64766
  • R64,766
  • R64766

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

96; was RISPERIDONE (NM) 1988-95

MeSH Record

Previous Indexing

  • Isoxazoles (1988-1995)
  • Piperidines (1988-1995)

MeSH Hierarchy

Tree Number

  1. D03w.383.742.698.685w

AMA Style

References

  1. National Library of Medicine. Risperidone. Medical Subject Headings (MeSH). 2026. Unique ID D018967. http://id.nlm.nih.gov/mesh/2026/D018967
  2. Risperidone. In: Wikipedia. https://en.wikipedia.org/wiki/Risperidone
  3. Risperidone. In: Wikidata. https://www.wikidata.org/wiki/Q412443
  4. Risperidone. In: PubChem Compound. CID 5073. https://pubchem.ncbi.nlm.nih.gov/compound/5073