Diseases

Rheumatoid Nodule

Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterized histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Subcutaneous nodules seen in 20-30% of rheumatoid arthritis patients. They may arise anywhere on the body, but are most frequently found over the bony prominences. The nodules are characterized histologically by dense areas of fibrinoid necrosis with basophilic streaks and granules, surrounded by a palisade of cells, mainly fibroblasts and histiocytes.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • Rheumatoid Nodulosis
  • Nodule, Rheumatoid
  • Nodules, Rheumatoid
  • Rheumatoid Nodules
  • Rheumatoid Noduloses

MeSH Record

Aspects Covered

35 allowable subheadings

Indexed with the subheadings blood, cerebrospinal fluid, chemically induced, classification, complications, congenital, diagnosis, diagnostic imaging, diet therapy, drug therapy, economics, embryology, enzymology, epidemiology, ethnology, etiology, genetics, history, immunology, metabolism, microbiology, mortality, nursing, parasitology, pathology, physiopathology, prevention & control, psychology, radiotherapy, rehabilitation, surgery, therapy, urine, veterinary, virology.

MeSH Record

Indexing Annotation

in rheum arthritis; do not confuse with RHEUMATIC NODULE in rheum fever

MeSH Record

History Note

67(63)

MeSH Hierarchy

Tree Numbers

  1. C05w.550w.114w.154w.683w
  2. C05w.799w.114w.683w
  3. C17.300w.775w.099w.683w

AMA Style

References

  1. National Library of Medicine. Rheumatoid Nodule. Medical Subject Headings (MeSH). 2026. Unique ID D012218. http://id.nlm.nih.gov/mesh/2026/D012218
  2. Rheumatoid Nodule. In: Wikipedia. https://en.wikipedia.org/wiki/Rheumatoid_nodule
  3. Rheumatoid Nodule. In: Wikidata. https://www.wikidata.org/wiki/Q1753520