Structured Summary
Abstract
A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. RBL2 contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and E2F5 TRANSCRIPTION FACTOR. RBL2 also interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
MeSH Record
Classification
Broader headings
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MeSH Record
Synonyms
5 entry terms
- RBL2 Protein
- Retinoblastoma Like Protein p130
- Retinoblastoma-Like Protein 2
- Retinoblastoma Like Protein 2
- p130, Retinoblastoma-Like Protein
MeSH Record
Aspects Covered
30 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1994)
MeSH Hierarchy
Tree Numbers
AMA Style
References
- National Library of Medicine. Retinoblastoma-Like Protein p130. Medical Subject Headings (MeSH). 2026. Unique ID D050717. http://id.nlm.nih.gov/mesh/2026/D050717
- Retinoblastoma-Like Protein p130. In: Wikidata. https://www.wikidata.org/wiki/Q7316792