Phenomena and Processes

Restriction Fragment Length Polymorphism

Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Variation occurring within a species in the presence or length of DNA fragment generated by a specific endonuclease at a specific site in the genome. Such variations are generated by mutations that create or abolish recognition sites for these enzymes or change the length of the fragment.

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Synonyms

4 entry terms
  • Polymorphism, Restriction Fragment Length
  • RFLP
  • RFLPs
  • Restriction Fragment Length Polymorphisms

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Aspects Covered

5 allowable subheadings

Indexed with the subheadings drug effects, genetics, immunology, physiology, radiation effects.

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History Note

95; was RESTRICTION FRAGMENT LENGTH POLYMORPHISMS 1987-94 (see under POLYMORPHISM (GENETICS) 1987-89)

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Previous Indexing

  • Chromosome Mapping (1971-1986)
  • DNA (1966-1971)
  • DNA Restriction Enzymes (1979-1986)
  • Endonucleases (1975-1977)
  • Genes, Structural (1977-1986)
  • Polymorphism (Genetics) (1980-1986)

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References

  1. National Library of Medicine. Restriction Fragment Length Polymorphism. Medical Subject Headings (MeSH). 2026. Unique ID D012150. http://id.nlm.nih.gov/mesh/2026/D012150
  2. Restriction Fragment Length Polymorphism. In: Wikipedia. https://en.wikipedia.org/wiki/Restriction_fragment_length_polymorphism
  3. Restriction Fragment Length Polymorphism. In: Wikidata. https://www.wikidata.org/wiki/Q857299