Chemicals and Drugs

Replisomes

A multienzyme complex that carries out DNA REPLICATION. Replisomes consist of DNA HELICASES; REPLICATION FACTOR C; PROLIFERATING CELL NUCLEAR ANTIGEN; DNA GYRASE; DNA TOPOISOMERASES; DNA LIGASES; and RIBONUCLEASE H.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A multienzyme complex that carries out DNA REPLICATION. Replisomes consist of DNA HELICASES; REPLICATION FACTOR C; PROLIFERATING CELL NUCLEAR ANTIGEN; DNA GYRASE; DNA TOPOISOMERASES; DNA LIGASES; and RIBONUCLEASE H.

MeSH Record

Classification

Related Concepts

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MeSH Record

Synonyms

5 entry terms
  • DNA Replisome
  • DNA Synthesome
  • Multiprotein DNA Replication Complex
  • Multiprotein Replication Complex
  • Replisome

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2026 (1997); use DNA SYNTHESOME (NM)1997-2025

MeSH Hierarchy

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AMA Style

References

  1. National Library of Medicine. Replisomes. Medical Subject Headings (MeSH). 2026. Unique ID D000099272. http://id.nlm.nih.gov/mesh/2026/D000099272
  2. Replisomes. In: Wikipedia. https://en.wikipedia.org/wiki/Replisome
  3. Replisomes. In: Wikidata. https://www.wikidata.org/wiki/Q22325217