Chemicals and Drugs

Raloxifene Hydrochloride

A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.

MeSH Record

Classification

Broader headings

Related Concepts

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

11 entry terms
  • Keoxifene Hydrochloride
  • Raloxifene HCl
  • Evista
  • Keoxifene
  • LY 139481
  • LY 156758
  • LY-139481
  • LY-156758
  • Raloxifene
  • LY139481
  • LY156758

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

2000; use RALOXIFENE (NM) 1983-1999

MeSH Record

Previous Indexing

  • Piperidines (1983-1999)

MeSH Hierarchy

Tree Number

  1. D02w.455w.426w.559w.389.150w.700w.900w.775

AMA Style

References

  1. National Library of Medicine. Raloxifene Hydrochloride. Medical Subject Headings (MeSH). 2026. Unique ID D020849. http://id.nlm.nih.gov/mesh/2026/D020849
  2. Raloxifene Hydrochloride. In: Wikidata. https://www.wikidata.org/wiki/Q27122215