Analytical, Diagnostic and Therapeutic Techniques, and Equipment

Radioimmunotherapy

Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Radiotherapy where cytotoxic radionuclides are linked to antibodies in order to deliver toxins directly to tumor targets. Therapy with targeted radiation rather than antibody-targeted toxins (IMMUNOTOXINS) has the advantage that adjacent tumor cells, which lack the appropriate antigenic determinants, can be destroyed by radiation cross-fire. Radioimmunotherapy is sometimes called targeted radiotherapy, but this latter term can also refer to radionuclides linked to non-immune molecules (see RADIOTHERAPY).

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Classification

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See Also

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Synonyms

3 entry terms
  • Immunoradiotherapy
  • Immunoradiotherapies
  • Radioimmunotherapies

MeSH Record

Aspects Covered

14 allowable subheadings

Indexed with the subheadings adverse effects, classification, economics, ethics, history, instrumentation, methods, mortality, nursing, psychology, standards, statistics & numerical data, trends, veterinary.

MeSH Record

Indexing Annotation

coordinate with disease /radiother

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History Note

92

MeSH Record

Previous Indexing

  • Antibodies, Monoclonal/therapeutic use (1984-1991)
  • Immunotherapy (1984-1991)
  • specific radioisotope/therapeutic use (1981-1991)

MeSH Hierarchy

Tree Numbers

MeSH Record

NLM Classification

QZ 270

AMA Style

References

  1. National Library of Medicine. Radioimmunotherapy. Medical Subject Headings (MeSH). 2026. Unique ID D016499. http://id.nlm.nih.gov/mesh/2026/D016499
  2. Radioimmunotherapy. In: Wikipedia. https://en.wikipedia.org/wiki/Radioimmunotherapy
  3. Radioimmunotherapy. In: Wikidata. https://www.wikidata.org/wiki/Q2126427