Structured Summary
Abstract
A metabolite of tryptophan with a possible role in neurodegenerative disorders. Elevated CSF levels of quinolinic acid are correlated with the severity of neuropsychological deficits in patients who have AIDS.
Chemical Identity
Chemical Information
- Molecular Formula
- C7H5NO4
- Molecular Weight
- 167.12 g/mol
- CAS Registry No.
- 89-00-9
- IUPAC Name
- pyridine-2,3-dicarboxylic acid
- InChIKey
- GJAWHXHKYYXBSV-UHFFFAOYSA-N
- SMILES
- C1=CC(=C(N=C1)C(=O)O)C(=O)O
- MeSH Unique ID
- D017378
- Source
- PubChem CID 1066
MeSH Record
Classification
Broader headings
Related Concepts
Knowledge Graph
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MeSH Record
Synonyms
4 entry terms
- Quinolinate
- Quinolinic Acid, Copper(2+) Salt
- Quinolinic Acid, Disodium Salt
- Quinolinic Acid, Strontium Salt
MeSH Record
Aspects Covered
25 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
History Note
93; was QUINOLINIC ACID (NM) 1981-92
MeSH Record
Previous Indexing
- Quinolinic Acids (1981-1992)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Quinolinic Acid. Medical Subject Headings (MeSH). 2026. Unique ID D017378. http://id.nlm.nih.gov/mesh/2026/D017378
- Quinolinic Acid. In: Wikipedia. https://en.wikipedia.org/wiki/Quinolinic_acid
- Quinolinic Acid. In: Wikidata. https://www.wikidata.org/wiki/Q411945
- Quinolinic Acid. In: PubChem Compound. CID 1066. https://pubchem.ncbi.nlm.nih.gov/compound/1066