Chemicals and Drugs

Pyrilamine

A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.

Chemical Identity

Chemical Information

Molecular Formula
C17H23N3O
Molecular Weight
285.4 g/mol
CAS Registry No.
91-84-9
IUPAC Name
N'-[(4-methoxyphenyl)methyl]-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine
InChIKey
YECBIJXISLIIDS-UHFFFAOYSA-N
SMILES
CN(C)CCN(CC1=CC=C(C=C1)OC)C2=CC=CC=N2
MeSH Unique ID
D011738
Source
PubChem CID 4992

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

9 entry terms
  • Mepyramine
  • Pyranisamine
  • Anthisan
  • Boots Bite & Sting Relief
  • Kriptin
  • Mepyramine Maleate
  • Pyrilamine Maleate
  • Maleate, Mepyramine
  • Maleate, Pyrilamine

MeSH Record

Aspects Covered

25 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, economics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

History Note

91(75); was see under AMINOPYRIDINES 1979-90; was see under PYRIDINES 1975-78

MeSH Record

Previous Indexing

  • Benzyl Compounds (1972-1974)
  • Ethylenediamines (1972-1974)
  • Pyridines (1970-1974)

MeSH Hierarchy

Tree Number

  1. D03w.383.725w.050.805w

AMA Style

References

  1. National Library of Medicine. Pyrilamine. Medical Subject Headings (MeSH). 2026. Unique ID D011738. http://id.nlm.nih.gov/mesh/2026/D011738
  2. Pyrilamine. In: Wikipedia. https://en.wikipedia.org/wiki/Mepyramine
  3. Pyrilamine. In: Wikidata. https://www.wikidata.org/wiki/Q3800087
  4. Pyrilamine. In: PubChem Compound. CID 4992. https://pubchem.ncbi.nlm.nih.gov/compound/4992