Chemicals and Drugs

Pyridoxal Phosphate

This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).

Chemical Identity

Chemical Information

Molecular Formula
C8H12NO7P
Molecular Weight
265.16 g/mol
CAS Registry No.
41468-25-1
IUPAC Name
(4-formyl-5-hydroxy-6-methyl-3-pyridinyl)methyl dihydrogen phosphate;hydrate
InChIKey
CEEQUQSGVRRXQI-UHFFFAOYSA-N
SMILES
CC1=NC=C(C(=C1O)C=O)COP(=O)(O)O.O
MeSH Unique ID
D011732
Source
PubChem CID 38882

MeSH Record

Classification

Broader headings

Related Concepts

Knowledge Graph

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Drug Class

Pharmacological Action

MeSH Record

Synonyms

5 entry terms
  • Pyridoxal 5-Phosphate
  • Pyridoxal-P
  • Phosphate, Pyridoxal
  • Pyridoxal 5 Phosphate
  • Pyridoxal P

MeSH Record

Aspects Covered

29 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analogs & derivatives, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.

MeSH Record

Indexing Annotation

deficiency: coordinate PYRIDOXAL PHOSPHATE /defic (IM) with VITAMIN B 6 DEFICIENCY (IM)

MeSH Hierarchy

Tree Numbers

AMA Style

References

  1. National Library of Medicine. Pyridoxal Phosphate. Medical Subject Headings (MeSH). 2026. Unique ID D011732. http://id.nlm.nih.gov/mesh/2026/D011732
  2. Pyridoxal Phosphate. In: Wikidata. https://www.wikidata.org/wiki/Q27888204
  3. Pyridoxal Phosphate. In: PubChem Compound. CID 38882. https://pubchem.ncbi.nlm.nih.gov/compound/38882