Chemicals and Drugs

Purinergic P2X4 Receptors

A widely distributed purinergic P2X receptor subtype that plays a role in pain sensation. P2X4 receptors found on MICROGLIA cells may also play a role in the mediation of allodynia-related NEUROPATHIC PAIN.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

A widely distributed purinergic P2X receptor subtype that plays a role in pain sensation. P2X4 receptors found on MICROGLIA cells may also play a role in the mediation of allodynia-related NEUROPATHIC PAIN.

MeSH Record

Classification

Broader headings

Related Concepts

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MeSH Record

Synonyms

7 entry terms
  • P2X4 Purinoceptor
  • P2X4 Receptor
  • Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4
  • Receptors, Purinergic P2X4
  • P2X4 Receptors, Purinergic
  • Purinoceptor, P2X4
  • Receptor, P2X4

MeSH Record

Aspects Covered

17 allowable subheadings

Indexed with the subheadings administration & dosage, analysis, biosynthesis, blood, chemistry, classification, deficiency, drug effects, genetics, history, immunology, isolation & purification, metabolism, physiology, radiation effects, therapeutic use, ultrastructure.

MeSH Record

History Note

2011

MeSH Hierarchy

Tree Numbers

  1. D12.776w.157w.530w.400w.400w.750w.400
  2. D12.776w.543w.550w.450w.500w.600w.400
  3. D12.776w.543w.585w.400w.500w.600w.400
  4. D12.776w.543w.750w.695w.700w.720w.250w.400
  5. D12.776w.543w.750w.720w.700w.720w.500w.400

AMA Style

References

  1. National Library of Medicine. Purinergic P2X4 Receptors. Medical Subject Headings (MeSH). 2026. Unique ID D058848. http://id.nlm.nih.gov/mesh/2026/D058848
  2. Purinergic P2X4 Receptors. In: Wikidata. https://www.wikidata.org/wiki/Q24722365