Structured Summary
Abstract
Derivatives of folic acid (pteroylglutamic acid). In gamma-glutamyl linkage they are found in many tissues. They are converted to folic acid by the action of pteroylpolyglutamate hydrolase or synthesized from folic acid by the action of folate polyglutamate synthetase. Synthetic pteroylpolyglutamic acids, which are in alpha-glutamyl linkage, are active in bacterial growth assays.
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Classification
Broader headings
Related Concepts
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Drug Class
Pharmacological Action
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Synonyms
6 entry terms
- Acids, Pteroylpolyglutamic
- Folate Polyglutamates
- Polyglutamate Folates
- Pteroylpolyglutamates
- Folates, Polyglutamate
- Polyglutamates, Folate
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, urine.
MeSH Record
Indexing Annotation
deficiency: coordinate PTEROYLPOLYGLUTAMIC ACIDS /defic (IM) with FOLIC ACID DEFICIENCY (IM)
MeSH Record
History Note
91(79); was see under FOLIC ACID 1979-90
MeSH Record
Previous Indexing
- Folic Acid (1966-1978)
- Glutamates (1966-1978)
MeSH Hierarchy
Tree Number
AMA Style
References
- National Library of Medicine. Pteroylpolyglutamic Acids. Medical Subject Headings (MeSH). 2026. Unique ID D011624. http://id.nlm.nih.gov/mesh/2026/D011624
- Pteroylpolyglutamic Acids. In: Wikidata. https://www.wikidata.org/wiki/Q76544407