Structured Summary
Abstract
A membrane-bound flavoenzyme that catalyzes the oxygen-dependent aromatization of protoporphyrinogen IX (Protogen) to protoporphyrin IX (Proto IX). It is the last enzyme of the common branch of the HEME and CHLOROPHYLL pathways in plants, and is the molecular target of diphenyl ether-type herbicides. VARIEGATE PORPHYRIA is an autosomal dominant disorder associated with deficiency of protoporphyrinogen oxidase.
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Classification
Broader headings
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Synonyms
7 entry terms
- Protoporphyrinogen Dehydrogenase
- Protoporphyrinogen IX Oxidase
- Protoporphyrinogenase
- Protox
- Dehydrogenase, Protoporphyrinogen
- Oxidase, Protoporphyrinogen
- Oxidase, Protoporphyrinogen IX
MeSH Record
Aspects Covered
28 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1975)
MeSH Record
Previous Indexing
- Oxidoreductases (1993-2003)
- Oxidoreductases Acting on CH-CH Group Donors (2004-2005)
- Porphyrins (1975-1976)
- Protoporphyrins (1975-1982)
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AMA Style
References
- National Library of Medicine. Protoporphyrinogen Oxidase. Medical Subject Headings (MeSH). 2026. Unique ID D050768. http://id.nlm.nih.gov/mesh/2026/D050768
- Protoporphyrinogen Oxidase. In: Wikidata. https://www.wikidata.org/wiki/Q24774393