Chemicals and Drugs

Proto-Oncogene Proteins c-ret

Receptor protein-tyrosine kinases involved in the signaling of GLIAL CELL-LINE DERIVED NEUROTROPHIC FACTOR ligands. They contain an extracellular cadherin domain and form a receptor complexes with GDNF RECEPTORS. Mutations in ret protein are responsible for HIRSCHSPRUNG DISEASE and MULTIPLE ENDOCRINE NEOPLASIA TYPE 2.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

Receptor protein-tyrosine kinases involved in the signaling of GLIAL CELL-LINE DERIVED NEUROTROPHIC FACTOR ligands. They contain an extracellular cadherin domain and form a receptor complexes with GDNF RECEPTORS. Mutations in ret protein are responsible for HIRSCHSPRUNG DISEASE and MULTIPLE ENDOCRINE NEOPLASIA TYPE 2.

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Synonyms

13 entry terms
  • Proto-Oncogene Protein Ret
  • Proto-Oncogene Protein c-ret
  • Receptor Tyrosine Kinase RET
  • c-ret Protein
  • ret Proto-Oncogene Proteins
  • Proto Oncogene Protein Ret
  • Proto Oncogene Protein c ret
  • Proto Oncogene Proteins c ret
  • Proto-Oncogene Proteins, ret
  • Ret, Proto-Oncogene Protein
  • c-ret, Proto-Oncogene Protein
  • c-ret, Proto-Oncogene Proteins
  • ret Proto Oncogene Proteins

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Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

MeSH Record

History Note

2006(1999)

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AMA Style

References

  1. National Library of Medicine. Proto-Oncogene Proteins c-ret. Medical Subject Headings (MeSH). 2026. Unique ID D051096. http://id.nlm.nih.gov/mesh/2026/D051096
  2. Proto-Oncogene Proteins c-ret. In: Wikipedia. https://en.wikipedia.org/wiki/RET_proto-oncogene
  3. Proto-Oncogene Proteins c-ret. In: Wikidata. https://www.wikidata.org/wiki/Q415976