Chemicals and Drugs

Proto-Oncogene Proteins c-myc

BASIC HELIX-LOOP-HELIX PROTEINS encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis.

National Library of MedicineMedical Subject Headings2026

Structured Summary

Abstract

BASIC HELIX-LOOP-HELIX PROTEINS encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis.

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Synonyms

21 entry terms
  • Proto-Oncogene Products c-myc
  • Proto-Oncogene Proteins myc
  • c-myc Proteins
  • myc Proto-Oncogene Product p62
  • myc Proto-Oncogene Proteins
  • p62 c-myc
  • p62(c-myc)
  • Proteins myc, Proto-Oncogene
  • Proto Oncogene Products c myc
  • Proto Oncogene Proteins c myc
  • Proto Oncogene Proteins myc
  • Proto-Oncogene Proteins, myc
  • c myc Proteins
  • myc Proto Oncogene Product p62
  • myc Proto Oncogene Proteins
  • myc, Proto-Oncogene Proteins
  • p62 c myc
  • L-myc Proteins
  • N-myc Proteins
  • L myc Proteins
  • N myc Proteins

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Aspects Covered

30 allowable subheadings

Indexed with the subheadings administration & dosage, adverse effects, agonists, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.

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History Note

91

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Previous Indexing

  • Neoplasm Proteins (1983-1984)
  • Phosphoproteins (1985)
  • Proto-Oncogene Proteins (1986-1990)

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References

  1. National Library of Medicine. Proto-Oncogene Proteins c-myc. Medical Subject Headings (MeSH). 2026. Unique ID D016271. http://id.nlm.nih.gov/mesh/2026/D016271
  2. Proto-Oncogene Proteins c-myc. In: Wikidata. https://www.wikidata.org/wiki/Q64901734