Structured Summary
Abstract
An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR SUPPRESSOR PROTEIN P14ARF.
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Classification
Broader headings
Related Concepts
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MeSH Record
Synonyms
11 entry terms
- Double Minute 2 Protein
- MDMX Protein
- Mdm-2 Protein
- Mdm2 Protein
- Murine Double Minute 2 Protein
- c-mdm2 Proto-Oncogene Protein
- Mdm 2 Protein
- Proto Oncogene Proteins c mdm2
- Proto-Oncogene Protein, c-mdm2
- c mdm2 Proto Oncogene Protein
- c-mdm2, Proto-Oncogene Proteins
MeSH Record
Aspects Covered
29 allowable subheadings
Indexed with the subheadings administration & dosage, adverse effects, analysis, antagonists & inhibitors, biosynthesis, blood, cerebrospinal fluid, chemical synthesis, chemistry, classification, deficiency, drug effects, economics, genetics, history, immunology, isolation & purification, metabolism, pharmacokinetics, pharmacology, physiology, poisoning, radiation effects, standards, supply & distribution, therapeutic use, toxicity, ultrastructure, urine.
MeSH Record
History Note
2006(1991)
MeSH Hierarchy
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AMA Style
References
- National Library of Medicine. Proto-Oncogene Proteins c-mdm2. Medical Subject Headings (MeSH). 2026. Unique ID D051736. http://id.nlm.nih.gov/mesh/2026/D051736
- Proto-Oncogene Proteins c-mdm2. In: Wikidata. https://www.wikidata.org/wiki/Q24783196